( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57



D. I. Adefokun*, E. O. Iwalewa, N. Omisore, F. O. Olorunmola, E.O. Akinkunmi, O. Iwalewa


This study evaluated the antimalarial effect of B. diffusa root extract on chloroquine sensitive P. falciparum. This was with a view to providing additional scientific information on its use as an antimalarial agent. The crude methanolic root extract of the plant was tested for its in vitro anti-plasmodial activity against Plasmodium falciparum (chloroquine-sensitive strain). In this study, 100 μl culture media were dispensed into a 96-well microtitre plate, leaving the ‘A’ series. Then, 100 μl of the test extract was pipetted into well ‘A’ and double fold serial dilutions were made down to well ‘H’. The last series 12 wells served as control. Twenty five (25) μl of infected red cells was separately added into all the wells in the test plates and mixed by swirling with the tips to ensure homogeneity and incubated at 370C in a candle jar and assessed for parasite growth after 27 h of incubation. The results of the in vitro assay showed that the methanolic extract of B. diffusa possessed weak antimalarial activity against P falciparum with IC50 of 55.35 μg/ml when compared with the standard antimalarial drug chloroquine whose IC50 was 0.5209 μg/ml. The antiplasmodial activity of the roots of the plant supports local claims on its efficacy in the treatment of malaria infection.

Keywords: Boerhaavia diffusa, Plasmodium falciparum, Malaria, Antiplasmodial activity.

[Full Text Article]



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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database