EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

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 ICV - 79.57

Abstract

EXTRACTION, PHYTOCHEMICAL EVALUATION AND CHARACTERIZATION OF POLYPHENOLS AND FLAVONOIDS FROM AQUEOUS METHANOLIC LEAF EXTRACTS OF INDIGENOUS PLANT CLERODENDRUM COLEBROOKIANUM WALP AND CENTELLA ASIATICA LINN OF NORTH EAST INDIA

Ratna Jyoti Das*, Daphisha Marbaniang and Bhaskar Mazumder

ABSTRACT

Extraction of polyphenols and flavanoids were done for two indigenous plants Clerodendrum colebrookianum walp and Centella asiatica. Extraction was done by both cold maceration and continuous hot percolation. Determination of total phenolic as well as and flavanoid content was carried out. Characterizations was done by TLC study, UV analysis, melting point determination and FTIR study. More total phenolic content found in Clerodendrum colebrookianum walp (621.02 ± 0.03 mg of GAE/gm plant extract) and content of total flavonoid was was found more in Centella asiatica L.(596.40 ± 0.53 mg of Quercetin equivalent/gm plant extract). UV and FTIR study concluded the existence of both flavonoids and phenolics in the respective extracts as compared with gallic acid and quercetin. Quantity of phenolic as well as flavanoid exhibit the indication of antioxidant action of the particular plants. Both the plants showing rich in total polyphenols and total flavonoids. Datas were mean ± SD moreover analyzed by means of One-way ANOVA, via Graphpad INSTAT. Confidence interval has been measured as 99% and p< 0.01 were considered significant. Phenolics encompass to possess an imperative antioxidant activity headed for free radicals, which is predominantly based on the redox properties of their phenolic hydroxyl groups and the structural associations among different parts of their chemical structure. It has been customary a highly positive rapport between total phenols along with antioxidant action in loads of plant species.

Keywords: Polyphenols, flavonoids, extraction, indigenous plant, phytochemical evaluation.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )