EVALUATION OF INVITRO ANTIOXIDANT ACTIVITY OF OXALIS LATIFOLIA KUNTH AND ITS ROLE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES

Arunkumar Subramanian*

ABSTRACT

Antioxidant plays an important role in inhibiting and scavenging free radicals, thus, providing protection to human against infection and Neurodegenerative diseases (NDD). Now the modern research is directed towards “Natural antioxidants” from the herbal plants due to safe therapeutic. In the present paper, we have investigated Antioxidant activity of extracts from Oxalis latifolia kunth for its free radical scavenging activity by adopting in vitro methods. The extracts were investigated for the antioxidant activity by 2, 2 - diphenyl, 1- picryl hydrazyl (DPPH) radical scavenging activity and Nitric oxide scavenging assay using Ascorbic acid as a standard compound. In the DPPH radical scavenging activity, the EEOL & AEOL have shown 90.39% & 86.34% inhibition of the DPPH radicals at 100 μg/ml concentration, whereas the standard (Ascorbic acid) has shown 96.42% inhibition at the same concentration. In the nitric oxide scavenging activity, the EEOL & AEOL have shown 76.37% & 68.14% inhibition of the nitric oxide radicals at 100 μg/ml concentration whereas the standard (Ascorbic acid) has shown 88.84% inhibition at the same concentration.

Keywords: Antioxidant, NDD, Oxalia latifolia kunth, DPPH radical scavenging activity, Nitric oxide scavenging assay.