COMPARISON OF THE EFFICIENCY OF ALOE VERA MOUTHWASH WITH ALCOHOL-FREE CHLORHEXIDINE ON PERIODONTAL DISEASE: A RANDOMIZED, DOUBLE- BLIND, CONTROLLED, CLINICAL TRIAL

Amirhossein Farahmand, Ferena Sayar*, Nafiseh Naghdi, Bahareh Jafrazadeh Esfahani and Navid youssefi

ABSTRACT

Background and Aim: the use of mouthwash has become Prevalent as a part of regular oral hygiene. Chlorhexidine has in fact been proven to be a gold standard oral care; the aim of this study was to compare the clinical periodontal parameters effectiveness and the side-effect profiles of an Aloe- Vera (AV) and an Alcohol-Free chlorhexidine (AF.CHX) -containing mouthwash. Methods and Materials: Using a double-blind, randomized clinical trial, a total of 32 healthy individuals with probing depth (PD) >4 mm and clinical attachment level (CAL) ≥1-3 mm; were allocated to treatment with SRP followed by Alcohol-Free chlorhexidine (CHX) mouthwash (A) or Aloe Vera (AV) mouthwash (B) for 15 days; Plaque index (PI) using a Silness & Loe index; bleeding index (BI) by Carter and Barnes; (PD), (CAL) were recorded at baseline and after 15 days. Adverse events were monitored. Results: (CHX) mouthwash reduced plaque formation significantly; (P<0.001). The decrease in BI score was greater in group A (0.02±0.03) compared to group B (0.13 ± 0.12) at 15 days; the meaningful reduction in PPD was in the (CHX) group was from 3.54± 0.58 to 1.69± 0.37 mm, meaningfully greater than with (AV) mouthwash; however Inter-group comparison showed that CAL was a significantly more meaningful reduction in CAL from baseline to 15 days in the (CHX) group than the (AV) group (P < 0.0001). Conclusions: (AV) mouthwash can be an effective antiplaque agent and with proper purification in taste, can be effective as adjunctive periodontal therapy; the two types of mouthwash seemed to be equally effective as antiplaque agents.

Keywords: Aloe Vera; Alcohol-Free chlorhexidine; periodontal diseases; mouthwash.