PREVALENCE AND PREDICTORS OF NON-ADHERENCE TO MEDICATION AMONG PATIENTS ON HEMODIALYSIS IN A TERTIARY CARE HOSPITAL, TAIF, KINGDOM OF SAUDI ARABIA

Majed Qalil Al-Orabi; (Pharm D) Nader NajiAlshalawi; (Pharm D) Mohmmed M. Alotaibi; (Pharm D) Mustafa Awad A Abdallah 5Prof. Yousif MA Dr. Abubaker Ibrahim Elbur

ABSTRACT

Background: Adherence to medication among patients on hemodialysis is an important issue for the delivery of optimum health care. Objectives: This study was conducted to measure the prevalence and to identify predictors of patients' non-adherence to drug therapy among patients on hemodialysis. Methods: A cross-sectional study was conducted at the Kidney Center at King Abdul Aziz Specialized Hospital;Taif;Saudi Arabia; during the September –November 2013. All adult patients on hemodialysis were included. Logistic regression analysis was performed. P value of < 0.05 was considered to be statistically significant. All statistical tests were conducted using the Statistical Package for Social Sciences (SPSS) version 21. Results: A total of 259 patients was included in the study. Males were 65.6%. The mean age was 48 + 16 years and > 60 years old patients were 26.6%. Nearly half of the patients (49.0%) had mild depression. Overall, 27.8% of the patients were found to be adherent to treatment. Multivariable analysis identified only three predictors that significantly associated with non- adherence to treatment, namely; younger age (< 50 years), (P<0.001), being a Saudi citizen (P = 0.001) and had no or minimal depression (P=0.025). Conclusions: Adherence to drug therapy among patients on hemodialysis was low. The identified predictors of non- adherence should be considered in any future interventions designed to improve patients' adherence to medications.

Keywords: Prevalence, Predictors Adherence, Medication, Hemodialysis.