SEROPREVALENCE & TRENDS OF TRANSFUSION TRANSMITTED INFECTIONS IN A TERTIARY CARE HOSPITAL

Dr. Shreya Patel*

ABSTRACT

Blood products are like double edged sword. Blood transfusion is linked to many of complications, some life threatening and life saving at same time. Transfusion Transmitted Infection (TTI) screening is vital step in pretransfusion tests.[1] Risk of TTI is a major drawback of transfusion. Vigilant donor selection helps improve blood safety. The prevention of transfusion-transmitted infection (TTI) is based on the exclusion of potential blood donors who are not fit and well, the education of donors to exclude themselves if they are at risk of contracting TTIs, the laboratory screening of all blood donations for evidence of infection with a range of potential TTIs, physical removal of white cells in those cases where the agent is cell associated, viral nactivation procedures for pooled plasma derivatives, detection of viral genomes in plasma pools and the avoidance of unnecessary transfusions.[2] Rapid testing is done for emergency purposes such as shortage of platelet concentrate, negative blood group units, SDPs, whole blood requirement, shortage of red cell concentrate.

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