HISTOMORPHOLOGICAL SPECTRUM OF RENAL TUMORS IN RESECTED NEPHRECTOMY SPECIMENS AT A TERTIARY CARE HOSPITAL

Deepti Agarwal, Prerna Mahajan*, Swaran Kaur, Kulwant Singh, Parveen Rana Kundu and
Ruchi Agarwal

ABSTRACT

Introduction: Renal tumour is 14th most common malignancy in the world of which mostly are of epithelial in origin (58%). It most commonly presents with a mass in abdomen or hematuria. Radical or partial nephrectomy is the treatment of choice and gold standard for a great proportion of patients with renal tumors. Aim and Objective: In this study our aim is to see the histomorphological spectrum of renal tumors in resected nephrectomy specimens at a tertiary care hospital and analyse the age distribution and various characteristics of renal tumors. Material and Methods: The study was carried out in Department of Pathology, B.P.S. Govt. Medical College, Khanpur Kalan. The resected nephrectomy specimens presented over a 6-year period from Jan 2012 to Oct 2017 were analysed retrospectively. All the patients with renal tumours managed surgically, were included. Results: A total of 20 cases were studied, 90% were malignant and 10% were benign. Male: female ratio was 1:1. 10 cases (50%) were attributed to renal cell carcinoma, while 4 cases (20%) Wilms tumour and 3 cases (15%) squamous cell carcinoma were reported. Conclusion: RCC is the most common histological type of renal neoplasm. Wilm’s tumour is the most common malignant renal tumour of childhood.

Keywords: Renal cell Carcinoma, Wilm’s Tumour, Nephrectomy.