UV SPECTROPHOTOMETRIC DETERMINATION OF CANDESARTAN CILEXETIL IN BULK DRUG
Parbati Kirtania Roy*, Nasema Begum and Mohd. Amrin Sultana
Candesartan Cilexetil (Candesartan) is a medication utilized for the treatment of Hypertension. It is in a class of
medication containing angiotensin receptor blocker (ARB). The main objective of the present work is to determine
a simple, precise and cost effective UV Spectrophotometric The wavelength of Candesartan Cilexetil using UV
Spectrophotometric was detected at 246nm in Acetonitrile and it obeys Beer’s law in a concentration range of 4-
24μg/ml with a correlation coefficient of 0.999. This method was validated for linearity, accuracy, precision, limit
of detection, limit of quantification. The %RSD was found to be <2.0% in all cases and all the validation
parameters were found to be within the limits. The proposed methods were suitable for the quantitative
determination of Candesartan Cilexetil in bulk drug.
Keywords: Candesartan Cilexetil, UV Spectrophotometer, Acetonitrile, Validation.
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