EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , 

 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57

Abstract

HEPATITIS B AND HUMAN IMMUNODEFICIENCY VIRUS (HIV) CO-INFECTION IN PORT HARCOURT METROPOLIS, NIGERIA: A COMPARISON OF THEIR RENAL INDICES ASSESSMENT

Ayodele Martins B. O., Adegoke Adebayo O., Olugbenga Bamigbowu, Aaron Umasoye U.* and Abah Austin

ABSTRACT

HIV and HBV co-infection has emerged over last two decades as a serious public health challenge. This study was done to determine the renal function indicators in subjects who are human immunodeficiency (HIV) and Hepatitis B surface antigen (HBsAg) positive. One hundred (100) subjects made up of Twenty five (25) each for HIV positive, Hepatitis B surface antigen positive and HIV-Hepatitis Virus (HBV) co-infected and HIV and HBsAg negative individuals (Controls) had their sodium, Potassium, Chloride, bicarbonate, Urea and creatinine determined using VITROS auto analyser 250/350/950/5, 1 FS and 4600 Chemistry Systems and the VITROS 5600 Integrated System manufactured by Ortho-Clinical Diagnostics, Inc. The results showed that there was significant difference (P<0.05) in sodium, Potassium, Chloride, bicarbonate concentrations of HIV positive, HBV positive and HIV-HBV co-infected patients when compared to their respective controls while there was no difference in their Urea and Creatinine concentrations. The study has shown that HIV and HBsAg positive and HIV-HBV co-infection cause electrolyte imbalance. Therefore, there is need for adequate awareness among health care providers and the public on the effect of the spread of these viral infections, the consequence of their co-infection and their modes of prevention.

Keywords: HIV, Hepatitis B, Infection, Renal Function, Port Harcourt.


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