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An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57



Stella Oyom Bassey, Onot Obono Ekpe and Augustine Lishilinimye Udefa*


This study assessed the microbial load of the colon of Wistar rats treated with Irvingia gabonensis seed extract (IGSex). Eight Wistar rats (200-250g) of both sexes were divided into two groups (n=4) thus: Normal group (received normal rat feed and water) and treated group (received 250mg/kg b.w. of IGSex in addition to normal feed and water). Treatment lasted for twenty-one days and was done twice daily via orogastric intubation. Rats were sacrificed under chloroform anaesthesia and each rat’s colon was removed and put in a well labeled sample container containing normal saline. Total anaerobes, bacteriodes, coliform and enterococcus were present and their concentrations significantly (p<0.05) increased in colon of rats in the treated group compared with those in the normal group. Lactobacillus was only very slightly increased in treated group compared with normal group. Carbohydrate such as cellulose, lignin, pectin and hemicellulose were present in the colon of rats in both groups. Resin was absent in the colon of rats in the normal group but present in the treated group. There was complete absence of fungi and starch in the colon of rats in both groups. All these carbohydrates and starch were present in the seed extract with hemicellulose and lignin occurring highest and lowest in concentration respectively. IGSex therefore increased the colonic load as well as the fermentation activity of microbes such as anaerobes, bacteriodes, coliform and enterococcus in Wistar rats.

Keywords: Carbohydrate; Colon; fermentation; Irvingia gabonensis; Microbe; rat.

[Full Text Article]



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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database