EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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Abstract

EFFECT OF CHOLECYSTECTOMY ON SERUM LIPID PROFILE PRE AND POST OPERATION

Prof. Dr. Raid M. H. Al-Salih*, Dr. Muhanad Abduredha and Sama Y. Yousif

ABSTRACT

Background: The objective of this study was to examine changes in body mass index (BMI). and to determine the changes in lipid profile parameters in three stages: preoperative, postoperative and long periods for cholecystectomy. Methods: Blood samples were collected from two groups of females (Women who will undergo their cholecystectomy as well as women who have been undergoing from cholecystectomy for a long time) with a total number of 128 women and 64 control females at AL-Hussein Teaching Hospital in Thi-Qar Governorate. from November 2017 to May 2018. Serum was separated by centrifugation and lipid profile (TC, TG, HDL, LDL, VLDL) were measured. The data were analyzed using SPSS. Results: Levels of BMI was significantly increased in all patient groups in comparison with control groups (p≤0.05). It was found significant differences in BMI between each of post (short and long terms) groups (p≤0.05). And the levels of serum TC, TG, LDL and VLDL were significantly increased in all patient groups in comparison with control groups (p≤0.05). It was found no significant differences in the concentration of serum TC, TG, LDL and VLDL between each of post (short and long terms) groups (p≤0.05). Also it was found significant differences in the concentration of serum TC, TG, LDL and VLDL between each of post (short and long terms) and control groups (p≤0.05). While levels of serum HDL was significantly decreased in all patient groups in comparison with control groups (p≤0.05). It was found no significant differences in the concentration of serum HDL between each of post (short and long terms) groups (p≤0.05). Also it was found a significant difference in the concentration of serum HDL between each of post (short and long terms) and control groups (p≤0.05). Conclusion: May be patients at risk of continuing to obesity as well as changes in some serum lipid profiles, long-term follow-up of these patients should be considered. The best solution is keeping a healthy diet and lifestyle after cholecystectomy. Follow-up long after the surgery may therefore be necessary to facilitate additional healthcare interventions.

Keywords: Body mass index, cholecystectomy, lipid profile.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia