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An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

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European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , 

 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57



Dr. Smruti Mohanty and Dr. Laxmi Kant Mohanty*


Intensive care unit (ICU) plays the important role in the management of critically ill patient admitted in ICU and prevention of the infection. Emergence of the antibiotic resistance is becoming increasingly difficult problems in ICU for preventions and resistance. Because of this there are few therapeutic options available. In ICU, Nosocomial infections with multidrug resistant are becoming important cause of death and morbidity compared with an average patient. Antibiotic resistance pattern of organisms widely vary for different country as well as different hospitals even among ICUs. The main purpose of this study was to know prevalence of the drug resistance pattern for the patients admitted in ICUs. Material and Methods: The study was done for 106 isolates from ICU of 80 patients. It was conducted at the Department of Microbiology, JLN Hospital and Research Centre, Bhilai. Sample for the culture were taken from ICU patient, depending upon the infection like ventilator associated pneumonia, respiratory tract infection, sepsis, and post operative patients. Specimens like urine, pus, blood and CSF etc. according to the type of infection. All the specimens were processed and Antibiotic susceptibility testing was done by Kirby-Bauer method using Muller Hinton Agar (MHA). Results: In vitro susceptibility data of 106 isolates from ICU were analysis. Among 106 isolates from 80 patients male were 52(65.0%) and 28 (35.0%) females. Out of 106 isolates 86(81.14%) were Gram negative organisms and 20(18.86%) were Gram positive organisms. Among all Gram positive organism 13(65%) were Staphylococcus aureus in which 8(61.53%) and 7.55% among all isolates respectively. The most frequent species isolated from infections in ICU was E.col , followed by Pseudomonas spp, klebsiella spp, Acinetobacter spp, Enterococcus , Proteus mirabilis and Providencia spp which were 18.87%, 16.03%, 16.03% , 6.60%, 1.89% and 0.94% respectively. 25(23.58%) were ESBL producer out of all isolate and 29.07% out of total Gram negative organism. Conclusion: This study concludes that gram negative organisms are causing more infection than gram positive organisms in ICU patients. E.coli was the most common organism isolated and shows highly resistance to Amoxcillin+Clavulanic acid, Ciprofloxacin whereas Erythromycin and Penicillin shows highly resistance to Enterococcus. Hence gram negative organisms are more resistance to higher antibiotics, so antibiotics are used carefully.

Keywords: ICU, Bacteria, AST, Resistance, Sensitivity.

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia