SYNTHESIS OF ROFLUMILAST IMPURITIES
K.Subhas Chander Reddy* and P. Kista Reddy
ABSTRACT
Roflumilast is a PDE-4 inhibitor with anti-inflammatory effect. Impurities observed during the synthesis and the other possible by products are identified. All the identified impurities are synthesized to have a better control over the synthesis of the Roflumilast.
Keywords: Roflumilast, impurities.
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