EFFECTS OF THE AQUEOUS EXTRACT OF THE STEMS BARK OF STRYCHNOS CAMPTONEURA GILG & BUSSE (LOGANIACEAE) ON THE FACTORS OF CARDIOVASCULAR RISK ETHANOL 20 %- INDUCED IN RAT

Etou Ossibi A.W.*, Morabandza C.J., Elion Itou R.D.G., Diassivi Madouda A.D., Ongoka P.R. and Abena A. A.

ABSTRACT

Currently, the alcoholic drinks are consumed abundantly in the big cities. Thus, the present survey has for objective to value the effects of the aqueous extract of the stems bark of Strychnos camptoneura on the cardiovascular factors of risk ethanol 20 % -induced in rat. The rats have been dealt daily with a solution of ethanol 20 % to 3.76 g/kg, orally during nine weeks concomitantly with the extract to the doses of 300 and 600 mg/kg/j, orally and water distilled to 10 ml/kg/j, per bone. The rats of the share witness had received the distilled water solely (10 ml/kg/j, orally). To the term of the nine weeks, the cardiovascular parameters of risk have been measured. The gotten results show that this excerpt opposes the gain weight, to the increase of the masses of the heart, the left ventricle and the report ventricle - bodily mass, to the high triglyceridemia and to the high blood sugar provoked by the ethanol 20 % whereas it is without effects on the concentration blood of total cholesterol and the creatinine. These results suggest that this excerpt corrects the cardiovascular factors of risk misled by the overcharge éthanolique 20 % at the rat. An ulterior survey on the parameters of stress oxidative of the organ seems useful.

Keywords: Ethanol 20 %, Strychnos camptoneura, weight, high triglyceridemia, the high blood sugar.