EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

GC-MS ANALYSES OF ETHYL ACETATE EXTRACT FROM LEAVES OF ABRUS PRECATORIUS L.- A MEDICINALLY IMPORTANT PLANT

Mohammed Shafi Sofi* and Shabnum Nabi

ABSTRACT

The present study investigated the chemical constituents of a traditionally used ethno-medicinal plant Abrus precatorius L. by preliminary phytochemical analysis and using a gas chromatography-mass spectrometry (GC/MS) analytical method. Ethyl acetate extract of A. precatorius (EAE-AP) leaves was prepared by using ethyl acetate solvent using a Soxhlet extractor for 16 h in soxhlet apparatus. GC-MS analysis of EAE-AP was performed using a Shimadzu Japan GC-2010 plus series apparatus. The spectrum of unknown component was compared with spectrum of the known components stored in National Institute of Standard and Technology (NIST) library; the name, molecular weight and structure of components in the test materials were ascertained. Preliminary phytochemical screening of the EAE-AP leaves by qualitative study revealed the presence of phytochemical alkaloids, flavonoids, saponins and triterpenoid/Steroids. Interestingly, twenty chemical constituents were identified in EAE-AP by GC-MS analyses. Many of these identified compounds are known to be having various pharmacological activities. Further by isolating and biologically characterizing these compounds, new drugs can be formulated to treat different life threatening diseases. The overall result obtained from this research suggested that A. precatorius may serve as a new potential source of medicines in the future.

Keywords: Abrus precatorius, GC-MS Screening and Phytochemical analysis.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )