( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57



Dr. A. Ravi, MD and *Dr. Jawahar Subbiah, MD


Introduction: Patients with chronic kidney disease (CKD) present with various clinical gastrointestinal (GI) symptoms and abnormalities in the GI tract. Studies on CKD patients are very few and there is not much Indian study to evaluate the frequency of these symptoms. This study was planned to our aim of this study is to evaluate the incidence of upper GI tract involvement in chronic renal failure patients. Also to find out any GI symptomatology in chronic renal failure patients with the upper gastro intestinal mucosal changes. Material and methods: The present study included 35 patients. In all patients a detailed history of the illness was taken with special reference to the gastro intestinal symptoms and subjected to a complete clinical examination. Blood urea, serum creatinine, creatinine clearance were measured and abdominal ultra-sonogram was performed. The patients were subjected to oesophago-gastro duodenoscopy. Endoscopic findings in oesophagus, stomach and duodenum were recorded. Results: In this prospective study, 26 were males and 9 were females. The age of the patients varied from 20 years to 70 years. The duration of illness varied from 3 months to 6 years. Their blood urea levels varied from 73% mgs to 196% mg. Serum creatinine ranged from 3.4 to 15.4 mgs. Their creatinine clearance from 2.8 ml to 29 ml. Nausea, vomiting, and anorexia were the most common symptoms; and erosive gastritis wes the most common endoscopic findings in CKD patients. Conclusion: Patients of chronic kidney disease frequently develop different GI symptoms and GI lesions. Persistence of endoscopic abnormality suggests that the improvement was not complete due to continued presence of uraemic toxins in non-dialysed patients. Early detection will be helpful in treating and improving the health status of the patients by reducing morbidity and mortality.

Keywords: Chronic kidney disease, haemodialysis, GI symptoms, GI endoscopy.

[Full Text Article]



  • New Issue Published

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    SEPTEMBER issue has been successfully launched on 1 SEPTEMBER 2023.

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database