ASSOCIATION OF PERIODONTAL INFECTIONS AND SYSTEMIC DISEASES: A REVIEW

*Dr. Ritu Phogat, Dr. Manjunath BC, Dr. Adarsh Kumar, Dr. Meenakshi Malik and Ms. Reena

ABSTRACT

An individual can‘t have general well-being without healthy periodontium. However, periodontal diseases are very common in developing and developed countries and periodontal infections are increasingly associated with systemic diseases. We aimed to evaluate the current literature on the association between periodontal infections and systemic diseases based on hill‘s criteria‘s. We searched the electronic database pubmed and google scholar over a time period of 20-year for studies on periodontal diseases and how they are associated with various systemic diseases. We examined the strength of association between periodontal disease and each systemic disease based on hills criteria of the dose–response relationship and the biological plausibility. We found that individuals with periodontal disease are at higher risk for adverse medical outcomes including cardiovascular diseases, respiratory infections, adverse pregnancy outcomes and diabetes mellitus. Many recent evidences from cohorts, in vitro and animal studies suggest that systemic inflammation due to pathogens associated with periodontal disease may play a role in the initiation and progression of particular systemic diseases. Periodontal infections are therefore considered as a risk factor for particular systemic diseases.

Keywords: Periodontium.