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An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57



Ali E. A.*, Iboyi, M. O. and Amuta, E. U.


Computer simulations have suggested that repeated Ivermectin treatment could suppress and subsequently interrupt transmission and has since been the main operational drug for the treatment and control of Onchocerciasis. In this study, the impact of Ivermectin on the prevalence of Clinical Onchocerciasis after two decades of mass drug administration was assessed. About 1014 Participants from 5 communities in Ushongo Local Government Area, who had received various rounds of Ivermectin were examined for Onchocercal depigmentation (Leopard skin), Onchodermatitis (Itching/Pruritis) and palpable nodules while ocular examination was carried out with illiterate e-chat and counting raised fingers at varying distances. Out of the 1014 volunteers, 219(21.6%) showed various symptoms of Onchocerciasis. A significant difference was observed (χ2 = 45.33, p < 0.05) in the prevalence of Clinical Onchocerciasis between the 5 communities. Farmers were the occupation most infected with 129(58.9%), Participants of age group ≥60 years were the most infected 22(47.7%), while the 11-20 years old were the least infected 18(11.7%). There was a significant difference between the prevalence of infection within the age groups (χ2 = 67.25, p < 0.05). 185 (84.5%) showed evidence of visual impairment, 170(79.8%) had Itching/Pruritis, 107(48.9%) had depigmentation /LS, 32(14.6%) had Onchocercal blindness and 59(26.9%) had Palpable nodules. Results obtained showed that there are significant reduction in the disease prevalence when compared to the REMO data prevalence of 48.58% after 20 years of Ivermectin chemotherapy. Ivermectin therefore remains an effective tool for the control of Onchocerciasis.

Keywords: Assessment, Ivermectin, Administration, Onchocerciasis, Community Treatment-seeking Behaviour, Ushongo.

[Full Text Article]




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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database