DYSLIPIDEMIA IN CHRONIC KIDNEY DISEASE POPULATION; A SINGLE CENTRE EXPERIENCE

*Afeaje B. Olokor (MBBS,FWACP,FMCP) and Evelyn I. Unuigbe (MBBS, DPH, FMCP, FWACP)

ABSTRACT

Background: Dyslipidemia is a major risk factor for cardiovascular disease in chronic kidney disease (CKD). Objectives: This study aimed at determining the prevalence of dyslipidemia among CKD patients in a tertiary hospital. Methodology: A comparative cross-sectional study of 160 CKD patients and an equal number of healthy controls. The Cockcroft-Gault formula was used in assessing renal function, lipid profile was also assessed and the National Cholesterol Education Program/Adult Treatment Panel III criteria used in the definition of dyslipidemia. Results: Mean age was 44.5 ± 15.7 years and 41.7 ± 14.6 years for cases and controls respectively. The prevalence of dyslipidemia was 94.4% amongst cases and 46.9% amongst controls with 73.1% of patients having reduced HDL-cholesterol, 66.2% elevated triglyceride, 25.6% elevated total cholesterol and 25% elevated LDL cholesterol in the CKD patients. The prevalence of dyslipidemia in the different stages of CKD I, II, III, IV and V were 33.3%, 66.7%, 94.2%, 97.5% and 95.2% respectively. Conclusion: Dyslipidemia is prevalent in CKD patients even in the early stages and becomes highly so as chronic kidney disease progresses.

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