EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database ,

ISSN 2394-3211

Impact Factor: 6.222

ICV - 79.57

Abstract

EFFECT OF CERTAIN POLYMERS ON PHYSICOCHEMICAL PROPERTIES OF TENOXICAM.

Esmat E. Zein, Mohamed A. Ossman, Shaimaa S. Mahmoud* and Heba A. Yassin

ABSTRACT

Tenoxicam is a widely used non-steroidal anti-inflammatory drug (NSAID). It is practically insoluble in water 14.1mg/ml, it is sparingly soluble in methylene chloride, very slightly soluble in ethanol and dissolves in solutions of acids and alkalis. The work in this study was performed in order to investigate the effect of certain polymers (Eudragit RL100, EudragitRS100 and methyl cellulose) in different drug to polymer ratios on the dissolution of tenoxicam in acidic as well as alkaline pH values. Solid dispersion technique was the technique of choice for preparing microbeads. FT-IR and X-ray diffraction were performed in order to investigate the interaction - if any- between the drug and the polymers.

Keywords: Tenoxicam, Eudragit RL100, Eudragit RS100, methyl cellulose, solid dispersion.

[Full Text Article]

SJIF Impact Factor: 6.222

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New Issue Published
Its Our pleasure to inform you that, EJPMR 1 September 2023 Issue has been Published, Kindly check it on https://www.ejpmr.com/issue

EJPMR: SEPTEMBER ISSUE PUBLISHED
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EJPMR New Impact Factor
Its our Pleasure to Inform you that EJPMR Impact Factor has been increased from 5.804 to 6.222, due to high quality Publication at International Level