EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

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 ICV - 79.57

Abstract

ULTRASONOGRAPHIC ANALYSIS IN CHOLELITHIASIS TO EVALUATE ITS IMPACT IN DIAGNOSIS, TREATMENT AND GALL STONE COMPOSITION

Dr. Urvil A. Shah* and Dr. Anil K. Shah

ABSTRACT

Introduction: Lifestyle and dietary habits of the patient are the most influencial factors for the formation of gall stones. Gallstones constitute a significant health problem in developed countries, affecting 10% to 15% of the adult population. In India prevalence of gall stones is 10 -20 %. Gallstones are common in the female population as compared to males. Formation of gallstones is due to inadequate physical activity, high waist hip ratio and excessive intake of saturated fats. Cholelithiasis is sometimes diagnosed in patients incidentally or as silent stones. Also they are reported in association with clinical symptoms such as cholecystitis and cholangitis. Ultrasound is the method having best sensitivity and specificity for evaluating patients with suspected gallstones. Material and Methods: The present study was carried out in the department of Radiology CCM Medical College and Hospital Kachandur, Durg. Total 150 patients were included in the study who were diagnosed of cholelithiasis. All patients underwent ultrasound examination prior to their surgery and histopathological analysis of gallbladder postoperatively. The gall stone was taken out and was further examined for bilirubin, calcium, cholesterol and phosphate. Results: 133 were positive for gallstones and 17 negative for gallstones. Out of 133 positive for gall stones 129 were confirmed by histopathology and 4 were found to have no gallstones on histopathology. Of the 17 ultrasound scans found to be negative for gallstone, no subsequent gallstones found on histopathology. As compared to histopathological reports sensitivity of ultrasonography was 100% (95% CI 97.18% to 100.00%). Specificity was 80.95 %( 58.09% to 94.55%). Positive Predictive Value 96.99 %( 95% CI 93.03% to 98.73%) and negative Predictive Value was 100.00 %. Accuracy of ultrasonography was 97.33% (95% CI 93.31% to 99.27%).Of the total histologically confirmed gallstones 20(15.03%) were cholesterol stone, 96 (74.04%) were mixed stone, while 13(10.34%) were pigment stone, Conclusion: Ultrasonography is accurate in diagnosing cholelithiasis and is considered the preferred initial imaging technique for patients who are suspected of having acute calculous cholecystitis.

Keywords: Ultrasound, gall stones.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )