EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

CUTANEOUS MALIGNANCY IN THE NIGERIAN ALBINO: A STUDY IN A TERTIARY URBAN HOSPITAL IN SOUTHERN NIGERIA

*Dr. Cynthia R. Madubuko and Emmanuel P. Kubeyinje

ABSTRACT

Background: Oculocutaneous albinism is an autosomal recessive disorder of pigmentation involving the skin, eyes, and hair. It is characterized by reduced or complete lack of melanin production. Melanin is protective against the harmful effects of the tropical sun. A lack of it predisposes the melanin deficient skin to cutaneous cancers. Aim: It determined the prevalence and pattern of cutaneous cancers in people with albinism living in Benin city. It also determined the relationship if any between cutaneous malignancy in them and the type of occupation, as well as use of sun protection methods. Methodology: This was a cross-sectional study conducted via a dermatological outreach albino clinic in the University of Benin Teaching Hospital in Southern Nigeria. A semi-structured questionnaire was used to collect data on sociodemographic characteristics. Also data regarding sun related dermatoses was collected and patients were examined thoroughly for cutaneous malignancy. Dermoscopy was used to boost diagnostic accuracy and skin biopsies were done to confirm diagnosis. Results: The prevalence of skin cancers was 9(12.4%) in the albino population and nil in their controls.p<0.01. Squamous cell carcinoma was the most common skin cancer observed in 8(11%) of the albinos.Conclusion: Cutaneous cancers are common in patients with albinism.The use of sun protective measures may reduce its incidence in them.

Keywords: Albinism; Cutaneous cancers, Melanin


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )