EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

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 ICV - 79.57

Abstract

PHYTOCHEMICAL EXAMINATION OF FLOWERS OF JASMINUM AURICULATUM VAHL

Yogendr Bahuguna* and Kaushal Kishore Chandrul

ABSTRACT

The aim of the present study was phytochemical investigation of extracts of flowers of Jasminum auriculatum Vahl. (Oleaceae). The alcoholic extract (AlcE, 10% w/v) of dried coarse powdered flowers was prepared using 70% v/v alcohol by soxhlet method at a temperature of 60-70°C (yield 5.4% w/w). The alcoholic extract (500 g) was divided into two equal portions. Each portion was suspended in distilled water (500 ml) and then extracted with petroleum ether (60 – 80°C, 8 X 500 ml) and ethyl acetate (8 X 500 ml) in succession. All the fractions were then washed with distilled water (30 ml), dried over anhydrous sodium sulphate and freed of solvent by distillation. The ethanol extract was thus fractioned into petroleum ether soluble fraction (40 g) and ethyl acetate soluble fraction (68 g). Chemical investigation of the flowers led to the isolation of three compounds namely lupeol, apigenin and quercetin. The constituents isolated and characterized from the Jasminum auriculatum flowers can be categorized under the triterpenes flavonoids. Triterpenes like lupeol were isolated from petroleum ether extracts and flavonoids like quercetin was isolated from the ethyl acetate extract and characterized by spectral data. In conclusion, Flavonoids like quercetin are believed to act as diuretic hence hastens the process of dissolving the preformed stones in curative regimen and prevention of new stone formation in urinary system on prophylactic treatment and as antioxidant agents, therefore may be useful in the treatment of urolithiasis, where lipid peroxidation is an important constituent. This investigation could conclude the antiurolithiatic property of J. auriculatum flowers due to the presence of flavonoids like quercetin.

Keywords: Jasminum auriculatum, Alcoholic Extract, Fractionation, Triterpenes, Flavonoids.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )