CASE REPORT ON THE EFFICACY OF LINEZOLID IN STAPHYLOCOCCAL SCALDED SKIN SYNDROME (SSSS) IN PEDIATRICS
Aisha Jalaludeen*, Nimmi Thomas and Saidali Mohammad
ABSTRACT
Staphylococcal scalded skin syndrome (SSSS) is a disorder that develops because of a toxin produced by a staphylococcal infection. Staphylococcus aureus is a bacterium commonly found harmlessly colonising human skin and mucosa without causing any morbidity. The symptoms of Staphylococcal scalded skin syndrome (SSSS) include blistering of skin on superficial layers due to the exfoliative toxins released from Staphylococcus aureus. Immediate medication with parenteral anti-staphylococcal antibiotics is mandatory. Mostly, SSSS are resistant to penicillin. Penicillinase resistant synthetic penicillins such as Nafcillin or Oxacillin are prescribed as emergency treatment medicine. If Methicillin-resistant Staphylococcus aureus (MRSA) is suspected), antibiotics with MRSA coverage (e.g., Vancomycin or Linezolid) are indicated. Clindamycin is considered as drug of choice to stop the production of exotoxin from bacteria ribosome. The case study is based on a pediatric patient admitted with Staphylococcal scalded skin syndrome (SSSS) in the Pediatric ICU of a tertiary care centre. This study aims to find out the effectiveness of Linezolid in reducing the symptoms of infection and recovery. This study was done by following up a pediatric patient admitted with SSSS and getting relevant details from medical records and caretaker interviews. From this study it was clearly evident that successful result was achieved in the case due to timely and correct management. This case report proves the effectiveness of Linezolid in cure of the disease.
Keywords: Staphylococcus aureus, Nafcillin or Oxacillin.
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