EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

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 ICV - 79.57

Abstract

A STUDY OF CLINICAL PROFILE OF DENGUE PATIENTS WITH SPECIAL REFERENCE TO HEPATIC DYSFUNCTION IN A TERTIARY CARE HOSPITAL IN NORTH KARNATAKA

*Dr. Khwaja M. Mohsin, Dr. M.V. Kalasuramath and Dr. Smrthi Shetty

ABSTRACT

Background: Dengue is a globally important arboviral infection transmitted by Aedes mosquitoes that endangers an estimated 2.5 billion people and represents a rapidly growing public health problem. There are between 50 and 100 million infections each year, with approximately 500,000 cases admitted to hospital with severe and potentially life threatening disease.[1] In our prospective study, 100 consecutive cases of dengue patients were studied. Patient underwent detailed clinical evaluation followed by laboratory investigations with special reference to hepatic dysfunction. Results: Male to female ratio was 2.3:1. Majority of the cases having dengue infection belong to the age group of 15-30 years. All the cases had fever (100%). Next common symptom in our study being vomiting (39%), headache (26%), abdominal pain (25%) and joint pain (20%). In our study, 32% clinically had hepatomegaly. Nearly 93% of the patients had thrombocytopenia. About 95% had deranged SGOT levels of which 22% had two and three times the normal range and 51% had more than three times the normal. Also 87% patients had deranged SGPT of which 41% and 21% had two and three times the normal levels and 25% had more than three times the normal level Conclusion: In adult patients with dengue infection, hepatic injury is nearly universal. Although in large majority of the patients it is asymptomatic, in some patients, it leads to clinical manifestations of liver disease keywords – Dengue, Hepatic dysfunction, Thrombocytopenia.

Keywords: .


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia