A REVIEW OF MANAGEMENT OF ATOPIC DERMATITIS
*Dr. Babitha M., Radhika B., Jincy Mary S. O. and Reshma V. H.
ABSTRACT
Atopic dermatitis (AD) is a chronic, relapsing skin disease characterized by itching, redness, edema, papulovesicles, scaling and dry lichenified skin which affects up to 20% of children and 1-3% of adult population. The main treatment regimen of atopic dermatitis include topical corticosteroids (betamethasone valerate), calcineurin inhibitors (tacrolimus, pimecrolimus), phototherapy and immunosuppressives (ciclosporin A, mycophenolate mofetil). Topical corticosteroids were considered as the first line agents. Calcineurin inhibitors were used in corticosteroid tolerated patients. New topical therapies like Phosphodiesterase inhibitors, Janus Associated Kinase-Signal Transducer and Activator of Transcription inhibitors and systemic therapies with Dupilumab, Lebrikizumab/Tralokinumab, Apremilast were also approved for the treatment of AD.
Keywords: Atopic dermatitis (AD), Topical corticosteroids (TCS), Topical calcineurin inhibitors, Immunosuppressives.
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