Ara-C SYDROME FOLLOWING LOW DOSE CYTARABINE INFUSION IN A CHILD TREATED FOR ACUTE MYELOID LEUKEMIA (AML)
Shehu U. Abdullahi* and Ahmed K. Abdulkareem
Cytarabine (Ara-C) syndrome is a rare condition characterized by acute febrile reaction, myalgia, bone pain and occasionally chest pain, maculopapular rash, conjuctivitis and malaise. This complication is mostly described with standard or high dose cytarabine infusion, and rarely following low dose cytarabine infusion. We report a case of 2 year old boy who developed cytarabin syndrome following low dose ara-C infusion as part of treatment for AML despite prior pre-medication with dexamethasone
Keywords: Ara-C syndrome, Low dose cytarabine, Dexamethasone, acute myeloid leukemia.
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