EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

MIDDLE EAR MUCOSA TUBERCULOSIS: A RARE CASE

Dr. Sunita Singh, Dr. Sakshi Dahiya, Dr. Bharti Sharma*, Dr. Rajeev Sen

ABSTRACT

Tuberculosis is a widely prevalent disease in developing countries. Tuberculous otitis media is a rare form of presentation of chronic otitis media and extrapulmonary Tuberculosis. Middle ear mucosa tuberculous infection can be acquired by hematogenous route and rarely by infection through middle ear perforation. The typical symptoms and signs which the patient presents with, include multiple perforations of the tympanic membrane, painful ear discharge, preauricular lymphadenopathy, sensorineural hearing loss and associated constitutional symptoms. Diagnosis is tricky because the cultures are usually negative and positive acid-fast bacilli smears are uncommon too. Also, histopathological examination rarely shows tubercular granulomas but more frequently indicate necrotising granulomas, if any. A case of 20 year old male, who presented with the complaint of on and off bilateral ear discharge since childhood, who clinically diagnosed as having bilateral chronic suppurative otitis media and his middle ear mucosa biopsy was taken and processed, microscopic examination done and biopsy comprised of mature cartilaginous tissue and soft tissue which was infilterated by mononuclear cells along with epithelioid cell granulomas, revealing focal necrosis. This was suggestive for tuberculosis. Tuberculosis is the most common infection worldwide. Fortunately, TB of the middle ear and temporal bone are rare. Disease is usually unilateral but this patient had bilateral ear involvement. Treatment includes surgical options like tympanoplasty and radical mastoidectomy. Tuberculosis of the ear is difficult to diagnose on biopsy but once established, it responds well to therapy. Hence treatment should be early and prompt so as to avoid other complications.

Keywords: Tuberculosis, Middle ear mucosa, chronic suppurative otitis media.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )