EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database ,

ISSN 2394-3211

Impact Factor: 6.222

ICV - 79.57

Abstract

GENES AND CELL SIGNALLING IN PROSTATE CANCER: A REVIEW

Gregory Elayeche Oko*, Emmanuel Paul Okoi, Maryam Ammani Lawal, Khuyen Thi Kim Vo, Margaret Akpana Odey and Trung Minh Dao

ABSTRACT

Cancer is a genetic disease linked with alteration or mutation of gene with multistep process for tumor development. The prostate cancer is globally rated as the second most common cancer. Typically, cancer occurs due to smoking and infectious diseases as well as chemicals and radiation. In this review we examine the function of various molecular and epigenetic genes associated with prostate cancer. An online search of current and past peer reviewed literature on cancer with emphasis on prostate was performed. We also discuss the functionality of the gland of prostate carryout by cell signalling. In conclusion, the various genes with diverse role at specific loci involved in prostate cancer are either overexpressed, down-regulated or inactivated at initiation stage or progression to metastasis with some being targeted for therapeutic purpose.

Keywords: Prostate cancer, TMPRSS2 gene, GSTP1 gene, androgen receptor signalling.

[Full Text Article]

SJIF Impact Factor: 6.222

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NEWS & UPDATION

EJPMR: JUNE ISSUE PUBLISHED
JUNE issue has been successfully launched on 1 JUNE 2023.

New Issue Published
Its Our pleasure to inform you that, EJPMR 1 June 2023 Issue has been Published, Kindly check it on https://www.ejpmr.com/issue

EJPMR New Impact Factor
Its our Pleasure to Inform you that EJPMR Impact Factor has been increased from 5.804 to 6.222, due to high quality Publication at International Level