FERUMOXYTOL: A REVIEW

Manjima G. S., Mridula Das, Julia J. J. and Neethu J.*

ABSTRACT

Ferumoxytol is a super paramagnetic iron oxide nanoparticle coated with a low molecular weight semi-synthetic carbohydrate. This drug is indicated for the treatment of iron deficiency anemia in adult patients who have experienced intolerance to oral iron or have experienced an unsatisfactory response to oral iron or who have chronic kidney disease (CKD). Iron deficiency anemia is a common complication in patients with chronic kidney disease (CKD). The recommended initial dose is a 510 mg intravenous injection followed by a second 510 mg intravenous injection 3 to 8 days later. Ferumoxytol is having similar effect and safety profile compared to other iron supplements. But in contrast, if patients are unresponsive or intolerant to oral iron supplements, ferumoxytol is a better choice and it does not have any serious adverse events. Ferumoxytol use can shorten the clinical visits of the patient as only two effective doses are required.

Keywords: Ferumoxytol, Iron Deficiency Anemia, Chronic Kidney Disease.