BIOLOGICAL POTENTIAL OF HETEROCYCLIC TRANSITION METAL COMPLEXES: A REVIEW
Shiwshankar N. Wangikar, Suresh G. Vedpathak and Mazahar Farooqui*
Transition metal complexes play an important role in medicinal inorganic chemistry. Due to the metal chelation, these compounds have attracted much attention in the development of new drug discovery. The use of heteroaryl ring system in metal chelation have attracted considerable attention owing to their unique properties as pHsensitive, photochromic, rodox responsive, stabilizes low valent metal oxidation states etc. The heterocyclic ligands and their metal complexes can be used as antimicrobial, antitumor, antihistaminic, antioxidative, antiinflammatory, analgesic and neuroprotective properties. The present review complies the recent progress in the biological activities of transition metal complexes bearing heterocyclic ligands.
Keywords: Anticancer, Antimicrobial, Heterocyclic ligands, Metal complexes.
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