AUTO ANTIBODY PROFILE IN PATIENTS WITH TUBERCULOSIS

Dr. Mohammad Hadi Faris* and Dr. Rokan M. Fadhil

ABSTRACT

Objective: To detect the prevalence of wide array of autoantibodies in sera of patients with tuberculosis compared with healthy control subject. Methods: Consecutive patients with recently diagnosed pulmonary and extra pulmonary {axial & peripherial joints TB}, mean age 36.2 years. 41 males and 21 females. the autoantibodies are R.F lgM, ANA, anti cls DNA. P-ANCA, ACL ENA {SSA SSB. RNP SM SCL70}. Results: Mean duration of symptoms 15.69 & 15.70(SD) months. 82% had fever, 39.3% had cough and hemoptysis. 27% had arthralgia and myalgia, 31.1% are diabetic and 24% are smoker serum level above the upeer normal limits were found in 25.7% of patients with RF, ANA was 8.8% , 20% , 6.3% in pulmonary, peripheral, axial TB respectively , P-ANCA 10%, 6.3% & for anti DNA was 5% , 10% 7 6.3% for pulmonary, peripheral & axial ACL was 33.3, 12.5 pulmonary, axial TB ENA was {SCL70 3.2%, SM 3.2% , RNP3.2%, SSA 8.1% SSB 6.5%} CONCLUSION ACL and RF was significant among different group.

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