EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

INTRANASAL DEXMEDITOMIDINE AND INTRANASAL MIDAZOLAM AS PREMEDICATION IN PEDIATRIC SURGICAL PATIENTS

Dr. Kharat Mohammed Bhat, Dr. Samiksha Khanooja* and Dr. Irshad Yousuf

ABSTRACT

Background: Many routes and drugs have been studied for premedication in pediatric surgical patients. Intranasal being one of them. Ease of administration makes it one of the preffered routes. Objectives: To evaluate the safety and efficacy of midazolam, and dexmedetomidine as intranasal premedication in paediatric surgical patients -to study their hemodynamics and respiratory consequences and post anaesthesia recovery in paediatric patients. Method: It was a prospective, randomized double blind study. 50 children aged 1 to 8 years were studied in each group(midazolam and dexmedetomidine). Results: The intranasal midazolam 0.2 mg/kg and dexmedetomidine 1.5 μg/kg produced effective and significant sedation which was seen at 30 min in dexmedetomidine group and at 15 min in midazolam groups and this change was maintained in all groups at 45 min and at the time of induction of anesthesia In conclusion Conclusion: we found that midazolam, and dexmedetomidine produced adequate sedation with little side effects. We prefer to use midazolam due its efficacy and safety as well as availability and its low price in comparison to dexmedetomidine. Overall recovery profile was better in the patients who received dexmedetomidine.

Keywords: Intranasal, dexmedetomidine, midazolam, premedication, pediatric.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )