EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia ,

ISSN 2394-3211

Impact Factor: 7.065

ICV - 79.57

Abstract

IN VITRO ANTHELMINTIC ACTIVITY OF NOVEL MANNICH BASES USING

Ch. M. M. Prasada Rao*, V. Nikitha, N. Datta Tejaswi, M. Saiteja, Adimulam Guruprakash and D.
Dhachinamoorthi

ABSTRACT

The present study is an attempt to explore the anthelmintic activity of Mannich bases against adult Indian earthworms, Pheretima posthuma. The time taken for each worm for paralysis and death were determined. Mannich condensed derivatives MB-06 show effective activity when compared to orientation of standard drug, Piperazine citrate. The time taken for paralysis and death with mannich base-6 at 80 mg/ml was comparable to standard Piperazine citrate.

Keywords: Anthelmintic Activity, Benzimidazole, O-Phenylene Diamine Docking, Tubulin.

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SJIF Impact Factor: 7.065

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Its Our pleasure to inform you that, EJPMR 1 May 2025 Issue has been Published, Kindly check it on https://www.ejpmr.com/issue

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EUROPEAN JOURNAL OF PHARMACEUTICAL AND MEDICAL RESEARCH