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An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57



Dr. Rajendran Subramaniam, MD. and *Dr. Swarnalatha, MD.


Importance: Dengue outbreaks occur in an unprecedented manner and cause a huge burden on health resources. Mortality is high among vulnerable population. Aim: To investigate the cause and clinical manifestations of a sudden upsurge of fever patients admitted to Govt Villupuram Medical college. Design: This is a prospective observational study of acute fever patients who got from September to November 2017. Setting and Participants: The study was conducted at Government Villupuram Medical College and Hospital, Southern India. All patients with more than 16 years of age, hospitalized with fever of < 7 days duration [oral temperature of 101*F at least once during admission. Results: A total of 240 patients were included in the study. The male to female ratio was approximately 2:1[male 65%[n=156], female 35%(n=84)]. The distribution of acute fever was Dengue 153, Enteric fever 9, Malaria 2, Scrub Typhus 2, other fevers [liver abscess, pneumonia,etc] 4 and undiagnosed 70[Figure 3].Symptom analysis into the illness into the illness revealed that only 3 were significantly associated with confirmed Dengue. These were giddiness 168(p<0.001), bleeding manifestations 133(p<0.001) and pruritis 57(p<0.01).The dominant physical examination findings which had a predictive value for Dengue were orthostatic hypotension 187(p<0.01), clinical shock 199(p<0.001) and bleeding manifestations 133(p<0.001). However Tourniquet test was positive only in 73(30.4%) of patients. Cumulatively their positive predictive value was >90%.The important laboratory findings associated with Dengue were thrombocytopenia, leucopenia and raised hematocrit[p<0.01]. Conclusion: In the recent Dengue outbreak in Villupuram District many insights were drawn as regards the predictive capacity of clinical signs and symptoms for dengue. The information gained could be used in the early diagnosis and triage of patients in resource poor settings.

Keywords: Dengue outbreak, Clinical features, Acute fever.

[Full Text Article]



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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database