DESIGN, SYNTHESIS AND BIOLOGICAL SCREENING OF NOVEL 4-THIAZOLIDINONES AGAINST PHERITIMA POSTHUMA AS HELMINITHESIS MODEL
Tribhuvan Singh*, Jogu Chandudru and Angothu Linganaik
The derivatives of 4-Thiazolidinone showed biological activity like antibacterial activities, antifungal, anticancer activity. In view of potential anthelmintic activities of 4-Thiazolidinone, derivative were prepared by Schiffâ€™s base technique. The compound were screened by anthelmintic activity, 4-Thiazolidinone also showed pharmacological activities, like antifungal, hypoglycemic activity, anti-convulsant activity, analgesic activity, anti-tubercular activity and anti-inflammatory activity. 4-Thiazolidinone also related five member rings, they are containing heterocyclic ring with nitrogen, oxygen and sulphur atom as well as thiazolidine ring.
Keywords: Sulphanilamide, Schiffs base, Thiazolidinone, Anthelmintic Activity.
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