PASS-ASSISTED PREDICTION OF BIOLOGICAL ACTIVITY SPECTRA OF METHANOLIC EXTRACT OF GYMNOPILUS JUNONIUS, A WILD MUSHROOM FROM SOUTHERN WESTERN GHATS, INDIA

Ragupathi V., Stephen A., Arivoli D. and Kumaresan S.*

ABSTRACT

Gymnopilus junonius was formerly known as Gymnopilus spectabilis, or Pholiota spectabilis v. junonia. This mushroom usually grows in clusters, but rarely grows solitary was collected from southern Western Ghats. This wild mushroom lacks evidence of scientific study and an attempt was made to identify the phytoconstituents present in it and their biological activity using PASS (Prediction of Activity Spectra for Substances). The most abundant constituents of this mushroom are Octadecanoic acid, 2,3-dihydroxypropyl ester, 1,4:3,6-Dianhydro-.alpha.-d-glucopyranose, Methyl stearate, 1,4:3,6-Dianhydro-.alpha.-d-glucopyranose, Benzeneacetic acid, D-Allose, Phenol, 2,4-bis (1,1-dimethylethyl), 1H-Imidazole, 4,5-dihydro-4-methyl-2-phenyl-, Octadecanoic acid, 2-hydroxy-1-(hydroxymethyl) ethyl ester and Octadecanoic acid. Our PASS-assisted prediction of biological activity spectra is the first report of this wild mushroom.

Keywords: Biological activity, PASS, Western Ghats, Mushroom.