EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

CHEMICAL COMPOSITION OF ESSENTIAL OIL OF CENTELLA ASIATICA L. BY GC-MS ANALYSIS

Undrala Sushen* and Awanija Chouhan

ABSTRACT

Centella asiatica (L.) (Umbelliferae), commonly known as gotukola or jalbrahmi in india. Centella asiatica (L.) is widely used for many pharmacological purposes in folk medicine, Ayurvedic, siddha, unani and now a days the compounds of Centella asiatica (L.) are also using in modern medicine to treat diseases related to nervous system, muscular system and blood vascular system etc. Centella asiatica (L.) is also used for treating Alzheimer’s diseases, Parkinson’s disease and Huntington’s disease. The extract was found to have neuroprotective ability through modifying a key signaling pathways and events concerned with neuro-degeneration. The essential oil of Ocimum gratissimum (L) exihibits considerable antibacterial, antifungal, anti tumor, antioxidant and many more activities. The present investigation has been carried out for the phytochemical study of leaf extract of Centella asiatica (L.). The essential oil is extracted by hydro distillation using Clevenger apparatus. The oil yield is observed to be 0.7 mL in 1 Kg. The essential oil is analyzed by GC and GC-MS instrumentation. Around 64 volatile compounds were identified from the essential oil of Centella asiatica (L.) P-Cymene (35%) is the predominant compound in the leaf essential oil of Centella asiatica (L.).

Keywords: Centella asiatica (L.), Essential oil, Clevenger apparatus, GC-MS analysis.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing