EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

COMPARISON OF INTRAMUSCULAR DEXAMETHSONE AND METHYLPREDNISOLONE IN CONTROL OF POST OPERATIVE SEQUALAE FOLLOWING SURGICAL EXCISION OF IMPACTED MANDIBULAR THIRD MOLARS

Dr. Velmurugan Naganathan*, Dr. K. Bala Vikhram and Dr. Vinod Narayan

ABSTRACT

Aim: The aim of this study was to compare the efficacy of dexamethasone with methylprednisolone with regards to postsurgical pain and swelling following third molar surgery. Material and Methods: 90 patients were divided into Group 1 (Dexamethasone) and Group 2 (Methylprednisolone). Following surgical removal of impacted third molar, each was administered either 8mg of dexamethasone or 40mg of methylprednisolone intramuscularly. Each patient was followed up and readings taken on the 1st, 3rd and 7th postoperative day. Variables recorded were swelling measured with a silk thread and calipers, and pain assessed via a Visual Analog Scale. Results: Out of the 90 patients, 47 were male and 43 female, with a mean age of 25 years. There was no stastistical significance between the two groups for both variables, except for swelling on the 1st postoperative day. The results indicated that dexamethasone is more effective at reducing postsurgical swelling on the 1st postoperativeday compared to methylprednisolone. (P<0.05). Conclusion: 8mg Dexamethasone is more effective than 40mg methylprednisolone at reducing swelling on the 1st postoperative day when administered intramuscularly. Both are equally effective at reducing postsurgical pain.

Keywords: Methylprednisolone; Dexamethasone; third molar surgery.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing