EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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ISSN 2394-3211

Impact Factor: 7.065

ICV - 79.57

Abstract

THE PREVALENCE OF THYROID DISORDERS AMONG PREGNANT WOMEN VISITING THE ANC OPD OF MAHATMA GANDHI MEDICAL COLLEGE AND HOSPITAL, JAIPUR

*Dr. Shivani Shekhawat, Dr. Swati Garg, Dr. Urvashi Sharma, Dr. Prateek Suren and Dr. Drishti Jain

ABSTRACT

Pregnancy is a physiological state, associated with significant, but reversible changes in thyroid function. There is a 10% increase in size of thyroid gland during pregnancy, as iodine requirement and production of thyroid hormone both increases during pregnancy. Maternal obstetric complications like hyperemesis gravidarum, abortions, pre- eclampsia, abruptio placenta, preterm labour, post partum thyroiditis, thyroid cancer and fetal complications like prematurity, low birth weight, still birth, perinatal death and respiratory distress syndrome are associated with thyroid disorders. Methods: For the prevalence of thyroid disorders during pregnancy, 2000 antenatal cases attending antenatal OPD at Mahatma Gandhi Medical College and Hospital, Jaipur, were studied. Detailed history, clinical examination and routine investigations were done along with thyroid profile. Results: In this study maximum number of patients,17% presented with subclinical hypothyroidism, 3% with subclinical hyperthyroidism,1% with overt hypothyroidism and no patient had overt hyperthyroidism. 9% of subclinical hypothyroidism had positive anti-TPO levels, while 33% of subclinical hyperthyroidism had positive anti-TPO levels. Highest number of patients were belonging to age group 21-25 years (46%) and lowest were under the age group >31 years (8%). Maximum number of patients (84%) were having normal BMI, underweight were (6.5%), overweight (9%) and obese(0.5%). Hindus were (83%), muslims (12%), christians(4%) and sikhs (2%). Conclusion: Looking at the high prevalence of thyroid disorders,21%,(majority being subclinical hypothyroidism 17%, and subclinical hyperthyroidism 3%), universal screening should be a part of routine antenatal investigations to avoid adverse maternal and fetal outcomes.

Keywords: Subclinical Hupothyroidism, Anti-TPO Levels, Antenatal Cases.

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