ANTIMICROBIAL POTENTIAL OF SCHIFF BASE METAL COMPLEXES: AN OVERVIEW
Rajkumar G. Momle, Suresh G. Vedpathak and *Gopal K. Kakade
The implication of metal chelation is carried in many important biological processes, where the coordination occurs
between different metal ions and a broad range of ligands. Coordination compounds have been considered as
characteristic compounds for bio-coordination compounds which controls the process of metabolism. Schiff bases
play a vital in the development of chemistry of coordination compounds. As the transition metal complexes
contribute a diverse and rich field of research, these complexes received much attention because of their
applications in biology, medicine and industry. Schiff bases and its transition metal complexes possess numerous
biological properties like antimicrobial, anti-inflammatory, anticancer, analgesic, anticonvulsant, antiviral,
anticonvulsant, anthelmintic, anti-HIV, antioxidant, and CNS depressant activities. The present review provides a
brief overview on the recent developments on antimicrobial potential of Schiff base transition metal complexes
reported in the last few decades.
Keywords: Antibacterial, Antifungal, Antimicrobial, Metal Complexes, Schiff base.
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