MICROENCAPSULATION TECHNIQUES IN PHARMACEUTICAL FORMULATION
Ayush Garg*, Kapil Chhipa and Lalit Kumar
Essentially microencapsulation is a process or technique by which thin coatings can be applied reproducibly to
small particles of solids, droplets of liquids, or dispersion, thus forming microcapsules. It can be differentiated
readily from other coatings methods in the size of the particle involved; these range from several tenths of a micron
to 5000μ in size. A number of microencapsulation processes have been discussed in the literature. Some are based
on chemically processes and involve a chemical or phase change; others are mechanical and require special
equipment to produce the physical change in the system require. The microencapsulation process provides answers
for problem such as masking the taste of bitter drugs, a means of formulating prolonged action dosage forms, a
means of separating incompatible material’s, a method of protecting chemicals against moisture or oxidation and a
means of modifying a materials’ physical characteristics for ease of handling in formulation and manufacture.
Keywords: Microencapsulation, Pan coating, Coacervation, Fluidized bed coating, Multi-orifice centrifugal technique.
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