EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

ROLE OF TOPICAL BEVACIZUMAB IN PREVENTION OF PTERYGIUM RECURRENCE AFTER SURGERY

Emad A. Saliem*, MD and Ahmed G. Elmahdy, MD.

ABSTRACT

Background: To evaluate the efficacy and tolerability of topical Bevacizumab 0.05% for treatment of 1ry pterygium and to detect the rate of recurrence after excision. Patients and Methods: This study included sixty eyes of 60 patients (37 males and 23 females) with primary pterygia. Thirty patients were considered as a control group (group A), received only topical antibiotic and steroid treatment for 1 month after pterygium excision with bare sclera technique, while the remaining thirty patient (group B) had received additional topical Bevacizumab 0.05% instillation for one month postoperatively. All patients were followed up for 6 months. During this period, the main outcome measures were corneal neovascularization, pterygium recurrence, and other postoperative complications. Results: The postoperative results revealed that after 6 months of follow-up: in (group A) there were 4 eyes (13.33%) showed recurrence which was not statistically significance different from group B which recorded 2 eyes recurrence (6.66%) P=0.4511 (>0.05). There were corneal neovascularization in 23 eyes (76.66%) in group A which was statistically significance different from group B which were 10 eyes (33.33%) P=0.018 (<0.05). Conclusion: Topical Bevacizumab for 1 month after surgical excision of pterygium with bare sclera technique is well tolerated and effective to prevent vascularization and reducing the recurrence rate after pterygium excision as it reduces the vascular element of the pterygium.

Keywords: Bevacizumab, pterygium.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing