EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

EVALUATION OF DIABETIC COMPLICATIONS, NEURO, HEPATO, CARDIO AND NEPHRO PROTECTIVE EFFECTS OF ETHANOLIC EXTRACT OF THE WHOLE PLANT OF TAXILLUS TOMENTOSUS IN ALLOXAN INDUCED DIABETIC RATS

Mohammed Nayeem Uddin*, Mohammed Wahab Uddin, Firasath Ali.

ABSTRACT

Diabetes mellitus (DM) is a world's fastest growing metabolic disease with high prevalence worldwide; associated with markedly increased morbidity and mortality rate and reduced the quality of life. It is the third commonest disease in the world affecting approximately 2.8% of global population. Persons with diabetes are at increased risk for macro vascular and micro vascular disease. Currently available synthetic antidiabetic agents produce serious side effects. This leads to a demand for herbal products with antidiabetic activity and fewer side effects. Hence the effects of oral administration of ethanolic extract of Taxillus tomentosus has been studied in alloxan induced diabetic Wister albino rats. The diabetic rats treated with ethanolic extract of whole plant of Taxillus tomentosus Tiegh with low dose and high dose, Metformin orally as an anti-hyperglycemic standard for 14 days. Test extract exhibited a significant dose dependent anti hyperglycaemic activity compared to diabetic control which is less potent than reference standard metformin. The results indicate that the ethanolic extract of Taxillus tomentosus is endowed with antidiabetic activity.

Keywords: Taxillus tomentosus, Hyperglycemia, Alloxan, Diabetic complications, allodynia.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )