EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , 

 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57

Abstract

THE INTRICACIES OF VITILIGO WITH REFERENCE TO RECENT UPDATES IN TREATMENT MODALITIES

Nargis Khan, Sharique A. Ali* and Naima Parveen

ABSTRACT

Vitiligo is a chronic stigmatizing human disease, affecting melanocytes from epidermis basal layer, leading to the development of hypochromic and achromic patches. Its estimated prevalence is 0.1-2% worldwide, regardless of race, gender or ethnic background. The deforming nature of vitiligo causes high psychosocial morbidity. Historically, the cause of vitiligo has been an extensive topic of debate. A wide range of theories have been put forward including genetic, autoimmune, melanocyte growth factors, autocytotoxic and neurogenic mechanisms. The current ‗state-of-the-art‘ thinking is summarised in the convergence theory which suggests that several factors can act synergistically or independently to induce the disappearance of melanocytes from the skin. Because of its complexity, several therapeutic options are available but the quest for an adequate treatment for vitiligo still continues. In this review, we have described the intrinsic and extrinsic factors that regulate human skin pigmentation, focusing on vitiligo and its least known intricacies. This article is dedicated to the introduction of and discussion about the most recent and innovative researches in the treatment of vitiligo.To assist further progress in vitiligo research, an overview on pathogenesis and recent updates on different nonsurgical and surgical treatment modalities are reviewed. It also provides a description of the newly developed techniques that are in the hands of dermatologists, dermato-cosmetologists, and dermatologic surgeons.

Keywords: Vitiligo, Melanocytes, Genetic, Autoimmune, Pathogenesis.


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  All Since 2019
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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia