EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , 

 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57

Abstract

ALTERATIONS OF MUSCLE FATIGABILITY AND EXERCISE CAPACITY AFTER MAXIMAL EXERCISE IN YOUNG ADULTS WITH CYSTIC FIBROSIS

Walid Kamal Abdelbasset*

ABSTRACT

Background: Cystic fibrosis is a genetic disorder affecting many physiological systems that may cause alterations of skeletal muscle strength, such as lowering of exercise capacity and impairment of physical activity. Objectives: The aim of this study was to investigate the effects of maximal exercise training on exercise capacity and muscle fatigability in cystic fibrosis young adults with moderate respiratory disease. Methods: Twenty eight young adults (18 ♂ and 10 ♀) were enrolled in the study. The study included two groups of young adults; the group of CF comprised of fourteen young adults with cystic fibrosis (9 ♂ and 5 ♀) and the group of healthy subjects comprised of fourteen age-matched healthy subjects (9 ♂ and 5 ♀). All participants have performed a maximal exercise test, muscle fatigue assessment, and cross-section area imaging. All measures were recorded and analyzed. Results: This study outcome demonstrated that there were lower FEV1, FVC, exercise capacity and had more oxygen desaturation with more breathing reserve index in young adults with CF than healthy subjects with p0.05. Conclusions: This study suggests that young adults with cystic fibrosis who had moderate pulmonary disorder and healthy subjects have similar effects in cross section area, muscle fatigability, and maximal contraction of the quadriceps muscle. Whereas maximal exercise has negative effects on exercise capacity in young adults with CF.

Keywords: Cystic fibrosis; Young adults; Maximal exercise; Exercise capacity; Fatigability.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia