EFFECT OF HIGH ETHANOL CONSUMPTION ON LIPID PEROXIDATION, LIPID PROFILE AND ALCOHOLICS RELATED COMPLICATIONS

Sangita Paneri, P. Dey Sarkar, Meena Verma and Shakti Suslade

ABSTRACT

Damaging effects of Reactive oxygen species are well studied. They include oxidative attack on various cell constituents. Chronic ethanol Administration may leads to increased free radical damages like cardiomyopathy. cardiomyopathy. In this study we investigate Lipid profile and oxidative stress. This study has been carried out on 100 subjects, who are alcoholic. Levels of total Cholesterol, Triglycerides, LDL, VLDL significantly high, and level of HDL were found to be decreased. The chronic alcoholic individuals were compared with non alcoholic controls. Our result suggests that alcohol administration causes myocardial injury through the induction of oxidative stress. Alcoholic individuals are more susceptible to developing cardiovascular diseases. Depression of antioxidant system proves to be a marker for oxidative injury caused by the administration of ethanol.

Keywords: OS – Oxidative Stress, MI – Myocardial Infarction, CVD – Cardio vascular disease, TAC-Total antioxidant capacity.