EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

THE OUTCOME OF PREGNANCY AMONGST HEPATITIS B VIRUS POSITIVE WOMEN IN A TERTIARY INSTITUTION IN NIGERIA

Umar Amina Gambo*, Ukwu Aaron Eze, Shehu Constance Egendu, Yakubu Abdulmuminu, Nasir Sadiya and Adoke Abdullahi Umar

ABSTRACT

Background: Hepatitis B Virus (HBV) infection occurs worldwide, and is particularly endemic in sub-Saharan
Africa. Viral hepatitis due to Hepatitis B infection has the same frequency in the pregnant and non - pregnant
populations. The aim of the study is to determine the outcome of pregnancy in the presence of HBV infection
among pregnant women attending the Ante-Natal Care clinic and to find out the risk factors for acquiring HBV
infection. Objectives: The aim of this study is to determine the prevalence and outcome of pregnancy in the
presence of Hepatitis B Virus infection among pregnant women attending Ante-Natal Care clinic of the Usmanu
Danfodiyo University Teaching Hospital, Sokoto. To find out the risk factors for acquiring the infection. Design: It
was a prospective study carried out from November 2012 to August 2013. Setting: Ante-Natal Care (ANC) clinic
of the Department of Obstetrics and Gynaecology Usmanu Danfodiyo University Teaching Hospita, Sokoto.
Nigeria. Subjects: Pregnant women attending antenatal care clinic. Intervention: Hepatitis B immunoglobulin
were administered to neonates of seropositive mothers Outcome Measures: Hepatitis B serology, mode of
delivery, gestational age at delivery, APGAR scores and birth weight. Result: The sero-prevalence of Hepatitis B
virus infection among the women was 7.7%. The seropositive mothers were found to have a twofold risk of
developing urinary tract infection (RR- 1.99. CI -0.53,7.44), though not statistically significant-P-value- 0.32).
However, there was no adverse maternal or fetal outcome and no identifiable risk factors among respondents.
Conclusion: Hepatitis B virus infection is endemic in our region, routine antenatal screening of pregnant women
and early active/passive immunisation of exposed neonates to reduce this rate in the unborn child is necessary.

Keywords: Pregnancy, Hepatitis B Virus Infection, Pregnancy Outcome.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )