EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

HYPONATREMIA: A CORRECTION DILEMMA

T. Tamilselvan*, Anju C. James, Arokia Rani C., Arya Jacob and Ashna Raj

ABSTRACT

Hyponatremia is a major problem associated with heart failure, with serum sodium concentration lower than 136 mmol/L. Hyponatremia has been reported as a risk factor for increased morbidity and mortality in patients with chronic heart failure. This case study, A 72-year-old female was admitted with the complaints of severe breathing difficulty and tiredness of 1-week duration. She had a past medical history of Diabetes mellitus and Hypertension. In last 2 years, she was suffering from DM with Nephropathy, Dilated Cardiomyopathy with Left Ventricular Dysfunction. The patient had a medication history of T.Amlodipine for hypertension and it may cause pedal edema and T.Losartan Potassium + Hydrochlorothiazide may cause hyponatremia. On admission, the patient has hypervolemic hyponatremia, after 2 days of treatment with Inj. Furosemide becomes euvolemic. Later the patient shows skin triggers which concluded hypovolemic hyponatremia and treated with inj. Furosemide and 3% hypertonic solution, it increases cardiac output through an increase in effective blood circulation volume, improve inappropriate elevation of AVP and enhance effects of diuretics. In conclusion, managing patient with heart failure associated with frequent hyponatremia is a difficult task which requires careful assessment and balancing of patient’s volemic condition and serum sodium level by properly adjusting the dose of dietary sodium, diuretic therapy along with fluid intake.

Keywords: Hyponatremia, Heart failure, Serum sodium.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )