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An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , 

 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57



Saima Shahid*, Nafeesa Kanwal, Farwa Hameed and Munaza Riaz


Objective: The aim of the study was to assess the prescribing trends of PPI’s and concomitant drugs in the Gastro esophageal reflux disease (GERD) patients and evaluation of success rate of drugs and patient compliance in hospitals of Punjab, Pakistan. Material and methods: Indiscriminate selection was made to select 300 patients diagnosed with GERD from various hospitals of Punjab, Pakistan. Patients and care takers were interviewed in very appropriate and agreeable manner to fetch the data on Questionnaire. The data was analyzed using statistical tools. Results were displayed in form of tables and graphs. Results: A total of 300 patients were observed in the outdoor and indoor departments of different tertiary care hospitals. Of the numbers of patients seen 10% patients had concurrent disease with GERD. 50% patients self-medicated themselves. Common symptoms associated with GERD were acid brash, dysphagia, heartburn and regurgitation. Most of the people (almost 55%) were using esomeprazole. Major side effect was GIT (Gastro Intestinal Tract) problems others include headache, allergy, pneumonia and osteoporosis. 19% patients have no effect on their quality of life, 37% feel better after treatment while 42% were curing from disease. 90% patients were following medication therapy and advice of physician. Only 10% patients were receiving pharmacist’s consultation. Conclusion: Esomeprazole, Omeprazole and Pantoprazole with some concomitant drugs were frequently prescribing medicines to treat GERD. Highly prescribed PPI was Esomeprazole with some of these medicines like Domperidone, Itopride, Mucaine, Gaviscone and Becefol to the patients. Some patients were not following the prescription accordingly. Lack of consultation, drug-drug interaction, underuse of drugs, in-appropriate use of drugs were some factors which leads to explore the risks of PPI’s. Appropriate treatment with PPI’s and concomitant medicines is a need to treat this effectively as it could become fatal disease and may lead to ulcer and cancer.

Keywords: GERD, Concomitant medicines with PPI’s, Efficacy, Quality, Side Effect.

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia